Dostarlimab is an immunotherapy agent utilized in the treatment of various cancers. This medication, classified as a monoclonal antibody, is primarily indicated for uterine or endometrial cancer, although it may also be effective against other cancer types. It can be administered as a standalone treatment or in conjunction with other therapies. Dostarlimab functions by modulating the immune response, enabling the body to target and eliminate cancer cells.
In India, the cost of Dostarlimab can fluctuate based on several factors, including the cancer stage and the specific combination of treatments employed. Each patient’s total expense may differ, as the Indian healthcare system adopts a personalized approach, tailoring treatment plans to meet the individual needs and conditions of each patient.
Overview of Dostarlimab
Dostarlimab functions by inhibiting the programmed death receptor-1 (PD-1) pathway, thereby enhancing the body’s immune response against cancer cells. By blocking this pathway, Dostarlimab allows T-cells to identify and attack malignant cells more effectively. Initially approved for treating recurrent or advanced endometrial cancer with specific genetic features, ongoing research is exploring its potential against other cancer types.
Dostarlimab Cost in India
Dostarlimab Cost in India starts from 10,000 USD (INR 8.55 Lakhs) and can cost up to 13,000 USD ( INR 11.1 Lakhs). There will be other related factors that will contribute to the final cost of Dostarlimab in India.
Dostarlimab Cost in India Vs Other Countries
| Countries | Prices |
| India | $11,000 |
| United State | $20,000 |
| United Kingdom | $19,000 |
| UAE | $16,000 |
| Australia | $17,500 |
These figures indicate that while Dostarlimab is more affordable in India compared to Western countries, it remains a substantial financial commitment.
Key Factors that is Influencing Dostarlimab Cost in India
Several variables can affect the overall expenses of Dostarlimab cost in India:
- Healthcare Professional’s Expertise: Experienced oncologists may charge higher consultation and procedural fees.
- Cancer Type and Stage: Advanced stages or aggressive cancer types might necessitate more intensive and prolonged treatment, increasing costs.
- Combination Therapies: Utilizing additional treatments alongside Dostarlimab can escalate expenses.
- Hospital Infrastructure: Facilities with advanced technology and comprehensive care services may have higher associated costs.
- Patient’s General Health: Pre-existing conditions or complications can lead to additional medical interventions, influencing the total expenditure.
Success Rates and Clinical Trials
Clinical studies have demonstrated promising results for Dostarlimab. For instance, a trial involving patients with mismatch repair-deficient stage II or III rectal adenocarcinoma showed that all participants experienced a complete clinical response, with no detectable tumors after six months of treatment. However, experts advise cautious optimism, emphasizing the need for larger, diverse studies and longer follow-up periods to confirm these findings
How is the Treatment Done?
The treatment protocol for Dostarlimab involves several stages:
Consultation with an Oncologist: A comprehensive evaluation, including medical history and diagnostic tests, determines the patient’s eligibility for the treatment.
Pre-Treatment Assessments: Necessary investigations, such as blood tests and imaging studies, are conducted to establish a baseline and identify any contraindications.
Dosage Administration: Typically, 500 mg of Dostarlimab is administered intravenously every three weeks for four cycles. Subsequent dosing depends on the patient’s response and overall health status.
Infusion Process: Each intravenous infusion lasts approximately 30 minutes to an hour, depending on individual tolerability.
Follow-Up Appointments: Regular monitoring ensures the treatment’s efficacy and allows for timely management of any adverse effects.
Combination Therapy: In certain cases, Dostarlimab may be combined with other treatments, such as chemotherapy or radiation, to enhance therapeutic outcomes.
Potential Side Effects
While Dostarlimab is generally well-tolerated, patients may experience side effects, including:
- Immune-Related Reactions: Such as pneumonitis, colitis, hepatitis, endocrinopathies, and nephritis.
- General Symptoms: Including fatigue, nausea, diarrhea, fever, and decreased appetite.
- Laboratory Abnormalities: Elevated liver enzymes or other blood test irregularities.
It’s crucial for patients to discuss potential risks with their healthcare providers and report any adverse symptoms promptly.
Takeaway
Dostarlimab represents a breakthrough in cancer immunotherapy, offering hope to patients with advanced malignancies. However, its cost remains a significant concern, especially in India, where financial constraints limit access to such cutting-edge treatments. While the price of Dostarlimab in India is lower than in Western nations, it is still a substantial investment for most patients.
For those considering this treatment, exploring financial aid programs, clinical trials, or government initiatives could help offset costs. Consulting with experienced oncologists and choosing reputed hospitals with immunotherapy expertise is crucial for optimal outcomes. As research progresses and production scales up, there is hope that Dostarlimab will become more affordable and accessible to a broader population in India.
A note from Hospitals India
At Hospitals India, our mission is to deliver precise and current information regarding medical treatments, including immunotherapy alternatives such as Dostarlimab. The price of Dostarlimab in India may fluctuate based on various factors, including the selected hospital, the expertise of the oncologist, and the specific needs of the patient. We advise consulting healthcare professionals to determine the most suitable treatment plan for your condition.
For those seeking tailored advice, cost assessments, or help in locating leading oncologists and hospitals in India, Hospitals India is here to assist. Our team is committed to connecting patients with reputable medical specialists to ensure optimal care.